KEGG   Homo sapiens (human): 51564
Entry
51564             CDS       T01001                                 
Symbol
HDAC7, HD7, HD7A, HDAC7A
Name
(RefSeq) histone deacetylase 7
  KO
K11408  histone deacetylase 7 [EC:3.5.1.98]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04613  Neutrophil extracellular trap formation
hsa05034  Alcoholism
hsa05203  Viral carcinogenesis
Drug target
Abexinostat (DG01402): D10060 D10084
Belinostat: D08870<US>
Bocodepsin (DG03260): D12551 D12552
Entinostat: D09338
Fimepinostat: D11319
Givinostat (DG03284): D12742 D12743<US>
Panobinostat (DG01403): D10019 D10319
Quisinostat (DG01407): D10321 D10322
Remetinostat: D10977
Romidepsin: D06637<JP/US>
Vorinostat: D06320<JP/US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    51564 (HDAC7)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    51564 (HDAC7)
  09165 Substance dependence
   05034 Alcoholism
    51564 (HDAC7)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    51564 (HDAC7)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     51564 (HDAC7)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     51564 (HDAC7)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 51564
NCBI-ProteinID: NP_001091886
OMIM: 606542
HGNC: 14067
Ensembl: ENSG00000061273
UniProt: Q8WUI4
Structure
Position
12:complement(47782722..47821344)
AA seq 954 aa
MHSPGADGTQVSPGAHYCSPTGAGCPRPCADTPGPQPQPMDLRVGQRPPVEPPPEPTLLA
LQRPQRLHHHLFLAGLQQQRSVEPMRLSMDTPMPELQVGPQEQELRQLLHKDKSKRSAVA
SSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPLETEGATRSMLSSFLPPVPSLP
SDPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKESAPPSLRRRPAETLGDSSPSS
SSTPASGCSSPNDSEHGPNPILGSEADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEA
GGTLPSRLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRS
EPLPPSATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQ
VVDDGLEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGH
RPLSRAQSSPAAPASLSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDN
SRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLK
LDNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELK
NGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF
YQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAF
RIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLA
LEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCM
QRLASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL
NT seq 2865 nt   +upstreamnt  +downstreamnt
atgcacagccccggcgctgatgggacccaggtgagcccgggtgcccactactgcagcccc
actggcgcaggctgccccaggccctgtgcagacacaccaggccctcagccgcagcccatg
gacctgcgggtgggccagcggcccccagtggagcccccaccagagcccacattgctggcc
ctgcagcgtccccagcgcctgcaccaccacctcttcctagcaggcctgcagcagcagcgc
tcggtggagcccatgaggctctccatggacacgccgatgcccgagttgcaggtgggaccc
caggaacaagagctgcggcagcttctccacaaggacaagagcaagcgaagtgctgtagcc
agcagcgtggtcaagcagaagctagcggaggtgattctgaaaaaacagcaggcggcccta
gaaagaacagtccatcccaacagccccggcattccctacagaaccctggagcccctggag
acggaaggagccacccgctccatgctcagcagctttttgcctcctgttcccagcctgccc
agtgaccccccagagcacttccctctgcgcaagacagtctctgagcccaacctgaagctg
cgctataagcccaagaagtccctggagcggaggaagaatccactgctccgaaaggagagt
gcgccccccagcctccggcggcggcccgcagagaccctcggagactcctccccaagtagt
agcagcacgcccgcatcagggtgcagctcccccaatgacagcgagcacggccccaatccc
atcctgggctcggaggctgacagtgaccgcaggacccatccgactctgggccctcggggg
ccaatcctggggagcccccacactcccctcttcctgccccatggcttggagcccgaggct
gggggcaccttgccctctcgcctgcagcccattctcctcctggacccctcaggctctcat
gccccgctgctgactgtgcccgggcttgggcccttgcccttccactttgcccagtcctta
atgaccaccgagcggctctctgggtcaggcctccactggccactgagccggactcgctca
gagcccctgccccccagtgccaccgctcccccaccgccgggccccatgcagccccgcctg
gagcagctcaaaactcacgtccaggtgatcaagaggtcagccaagccgagtgagaagccc
cggctgcggcagataccctcggctgaagacctggagacagatggcgggggaccgggccag
gtggtggacgatggcctggagcacagggagctgggccatgggcagcctgaggccagaggc
cccgctcctctccagcagcaccctcaggtgttgctctgggaacagcagcgactggctggg
cggctcccccggggcagcaccggggacactgtgctgcttcctctggcccagggtgggcac
cggcctctgtcccgggctcagtcttccccagccgcacctgcctcactgtcagccccagag
cctgccagccaggcccgagtcctctccagctcagagacccctgccaggaccctgcccttc
accacagggctgatctatgactcggtcatgctgaagcaccagtgctcctgcggtgacaac
agcaggcacccggagcacgccggccgcatccagagcatctggtcccggctgcaggagcgg
gggctccggagccagtgtgagtgtctccgaggccggaaggcctccctggaagagctgcag
tcggtccactctgagcggcacgtgctcctctacggcaccaacccgctcagccgcctcaaa
ctggacaacgggaagctggcagggctcctggcacagcggatgtttgtgatgctgccctgt
ggtggggttggggtggacactgacaccatctggaatgagcttcattcctccaatgcagcc
cgctgggccgctggcagtgtcactgacctcgccttcaaagtggcttctcgtgagctaaag
aatggtttcgctgtggtgcggcccccaggacaccatgcagatcattcaacagccatgggc
ttctgcttcttcaactcagtggccatcgcctgccggcagctgcaacagcagagcaaggcc
agcaagatcctcattgtagactgggacgtgcaccatggcaacggcacccagcaaaccttc
taccaagaccccagtgtgctctacatctccctgcatcgccatgacgacggcaacttcttc
ccggggagtggggctgtggatgaggtaggggctggcagcggtgagggcttcaatgtcaat
gtggcctgggctggaggtctggacccccccatgggggatcctgagtacctggctgctttc
aggatagtcgtgatgcccatcgcccgagagttctctccagacctagtcctggtgtctgct
ggatttgatgctgctgagggtcacccggccccactgggtggctaccatgtttctgccaaa
tgttttggatacatgacgcagcaactgatgaacctggcaggaggcgcagtggtgctggcc
ttggagggtggccatgacctcacagccatctgtgacgcctctgaggcctgtgtggctgct
cttctgggtaacagggtggatcccctttcagaagaaggctggaaacagaaacccaacctc
aatgccatccgctctctggaggccgtgatccgggtgcacagtaaatactggggctgcatg
cagcgcctggcctcctgtccagactcctgggtgcctagagtgccaggggctgacaaagaa
gaagtggaggcagtgaccgcactggcgtccctctctgtgggcatcctggctgaagatagg
ccctcggagcagctggtggaggaggaagaacctatgaatctctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Drug (16)   
   KEGG DRUG (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (28)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (26)   
DNA sequence (75)   
   RefSeq(nuc) (29)   
   GenBank (23)   
   EMBL (23)   
3D Structure (5)   
   PDB (5)   
Protein domain (1)   
   Pfam (1)   
All databases (172)   

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